The PNH Research and Support Foundation

PO Box 10983
Rockville, MD 20849

ph: 888-582-9993
fax: 888-582-9993

Medical Research

A primary goal of the PNH Foundation is to fund urgently needed medical research into finding new treatments, and ultimately a cure, for PNH disease. We are currently funding the following research studies:

  • Research Grant to Kazuhiko Ikeda, MD, PhD, Department of Hematology, Washington University School of Medicine, St. Louis, Missouri

    The Mechanism of Clonal Dominance of PNH Cells:

    Dr. Ikeda will be studying how PNH blood cells acquire a "growth advantage" through a gene mutation.  His findings are likely to provide new insights into the role of gene expression in clonal blood disorders such as PNH and MDS.

  • Research Grant to Regis Peffault de Latour, MD, PhD, Hematology Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland

    The Role of Unfolded Protein Response in PNH:

    Dr. Peffault de Latour’s study will examine the role of the Unfolded Protein Response (UPR) in the development of PNH cells. Understanding how the UPR allows for cell adaptation instead of cell self-destruction could lead to the discovery of new therapeutic strategies which target this pathway.

 

 

Copyright  2009 PNH Research and Support Foundation. All rights reserved.

 

PO Box 10983
Rockville, MD 20849

ph: 888-582-9993
fax: 888-582-9993